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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCN8ASodium channel protein type 8 subunit alpha isoform X1. (1992 aa)    
Predicted Functional Partners:
UNC79
Protein unc-79 homolog isoform X1.
   
 0.992
SCN1B
Voltage-gated sodium channel type I beta.
   
 0.974
SCN2B
Voltage-gated sodium channel type II beta.
   
 0.965
SCN4B
Voltage-gated sodium channel type IV beta.
    
 0.956
SCN3B
Voltage-gated sodium channel type III beta.
   
 0.945
SCN4A
Sodium voltage-gated channel alpha subunit 4.
  
 
0.913
SCNN1B
Amiloride-sensitive sodium channel subunit beta.
     
 0.889
SCNN1G
Sodium channel epithelial 1 gamma subunit.
     
 0.889
CACNA1G
Calcium voltage-gated channel subunit alpha1 G.
   
0.786
CACNA1I
Voltage-dependent T-type calcium channel subunit alpha-1I isoform X1.
   
0.747
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.