Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
SCN8ASodium channel protein type 8 subunit alpha isoform X1. (1992 aa)    
Predicted Functional Partners:
SCN2B
Voltage-gated sodium channel type II beta.
   
 0.929
PDLIM3
PDZ and LIM domain 3.
   
  
 0.906
DIS3
Exosome complex exonuclease DIS3/RRP44.
      
 0.902
SCN1B
Voltage-gated sodium channel type I beta.
    
 0.858
UNC79
Protein unc-79 homolog isoform X1.
   
 0.849
SCN4A
Sodium voltage-gated channel alpha subunit 4.
   
  0.814
SCN3B
Voltage-gated sodium channel type III beta.
   
 0.808
SCN4B
Voltage-gated sodium channel type IV beta.
    
 0.740
CCKBR
Gastrin/cholecystokinin type B receptor isoform X1.
   
 
 0.706
ADCY1
Adenylate cyclase type 1.
   
  
 0.702
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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