Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LIG1DNA ligase 1 isoform X1. (919 aa)    
Predicted Functional Partners:
PCNA
Proliferating cell nuclear antigen isoform X1.
   
 0.996
POLB
DNA polymerase beta.
  
 0.981
APEX1
DNA-(apurinic or apyrimidinic site) lyase.
  
 
 0.973
RFC4
Replication factor C subunit 4 isoform X1.
   
 0.951
XRCC1
DNA repair protein XRCC1 isoform X1.
   
 0.950
POLD1
DNA polymerase delta catalytic subunit.
   
 0.943
MCM5
DNA replication licensing factor MCM5.
   
 
 0.939
LOC110090970
Flap endonuclease 1-like.
  
 0.921
FEN1
Flap endonuclease 1.
  
 0.921
RFC3
Replication factor C subunit 3 isoform X1.
   
 0.920
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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