Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
C11orf53Uncharacterized protein C11orf53 homolog. (236 aa)    
Predicted Functional Partners:
POU2F3
POU class 2 homeobox 3.
    
 
 0.849
POU2F2
POU domain, class 2, transcription factor 2 isoform X1.
    
 
 0.703
POU2F1
POU domain, class 2, transcription factor 1 isoform X1.
    
 
 0.703
COLCA2
Colorectal cancer-associated protein 2.
      
 0.622
LOC110084991
Serum amyloid P-component-like isoform X1.
      
 0.619
POU1F1
Pituitary-specific positive transcription factor 1.
    
 
 0.521
POU3F2
POU domain, class 3, transcription factor 2.
    
 
 0.488
ENSPVIP00000021367
annotation not available
    
 
 0.488
ENSPVIP00000027985
POU domain, class 3, transcription factor 3-like.
    
 
 0.488
POU3F3
POU domain, class 3, transcription factor 3.
    
 
 0.488
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.