Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
SIK2Serine/threonine-protein kinase SIK2. (836 aa)    
Predicted Functional Partners:
CRTC2
CREB regulated transcription coactivator 2.
    
 
 0.943
PPP2R2C
Protein phosphatase 2, regulatory subunit B, gamma isoform X1.
   
  0.885
VCP
Transitional endoplasmic reticulum ATPase isoform X1.
    
 
 0.864
LOC110082643
Transitional endoplasmic reticulum ATPase-like.
    
 
 0.740
PPP2R2D
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform isoform X1.
   
  0.644
PPP2R1A
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform.
   
  0.633
SFN
14-3-3 protein sigma.
    
 0.587
YWHAQ
14-3-3 protein beta/theta/zeta.
    
 0.587
GTF2F2
General transcription factor IIF subunit 2.
     
  0.555
ENSPVIP00000016675
annotation not available
     
  0.555
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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