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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DLATPyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase). (546 aa)    
Predicted Functional Partners:
DLD
Dihydrolipoyl dehydrogenase, mitochondrial.
 0.999
PDHB
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial.
 
 0.999
PDHA1
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial isoform X1.
  
 0.999
PDHX
Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex.
  
0.998
CS
Citrate synthase, mitochondrial isoform X1.
  
 0.991
SUCLG1
Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial.
  
 0.986
ACLY
ATP citrate (pro-S)-lyase.
  
 0.981
PDK3
Pyruvate dehydrogenase kinase, isozyme 3 isoform X1.
    
 0.965
BCKDHA
2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial.
 
 0.962
BCKDHB
2-oxoisovalerate dehydrogenase subunit beta, mitochondrial.
 
 0.958
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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