Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EPN2Epsin-2. (598 aa)    
Predicted Functional Partners:
EPS15
Epidermal growth factor receptor substrate 15.
   
 0.950
EPS15L1
Epidermal growth factor receptor substrate 15-like 1.
   
 0.950
EPN3
Epsin-3 isoform X1.
  
 
0.941
EPN1
Epsin-1 isoform X1.
  
  
 
0.902
ITSN2
Intersectin-2 isoform X1.
    
 0.890
GAK
Cyclin-G-associated kinase isoform X1.
   
 0.888
CLTA
Clathrin light chain A isoform X1.
    
 0.865
CLTB
Clathrin light chain B isoform X1.
    
 0.865
AP2A2
AP-2 complex subunit alpha-2 isoform X1.
   
 0.864
AP2A1
AP-2 complex subunit alpha-1 isoform X1.
   
 0.813
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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