Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RAPH1Ras-associated and pleckstrin homology domains-containing protein 1-like. (1265 aa)    
Predicted Functional Partners:
NCK2
Cytoplasmic protein NCK2.
    
 
 0.872
ABI1
Abl interactor 1 isoform X1.
   
 
 0.832
VASP
Vasodilator-stimulated phosphoprotein.
    
 
 0.729
ENSPVIP00000027648
annotation not available
    
 
 0.729
RAP1A
Ras-related protein Rap-1A isoform X1.
    
 0.726
RAP1B
Ras-related protein Rap-1B.
    
 0.726
PFN4
Profilin-4.
    
 
 0.660
ENSPVIP00000007480
Rho guanine nucleotide exchange factor 40-like.
      
 0.632
TLN2
Talin-2.
    
 0.619
TLN1
Talin 1.
    
 0.619
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
Server load: low (38%) [HD]