Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ATRXTranscriptional regulator ATRX isoform X1. (2342 aa)    
Predicted Functional Partners:
DAXX
Death domain-associated protein 6 isoform X1.
    
 0.998
RAD51
DNA repair protein RAD51 homolog 1.
   
 0.990
SUPT16H
FACT complex subunit SPT16.
   
 
 0.913
MECP2
Methyl CpG binding protein 2.
    
 0.909
RAD52
DNA repair protein RAD52 homolog isoform X1.
    
 
 0.903
MRE11
Double-strand break repair protein MRE11.
  
 
 0.892
NBN
Nibrin isoform X1.
    
 
 0.891
SSRP1
Structure-specific recognition protein 1.
    
 
 0.890
TP53
Cellular tumor antigen p53.
    
 0.849
SMC5
Structural maintenance of chromosomes protein 5 isoform X1.
  
 0.833
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
Server load: low (10%) [HD]