Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TDP1Tyrosyl-DNA phosphodiesterase 1 isoform X1. (599 aa)    
Predicted Functional Partners:
LIG3
DNA ligase 3.
   
 
 0.980
POLB
DNA polymerase beta.
    
 
 0.963
TOP1
DNA topoisomerase I.
    
 
 0.961
XRCC1
DNA repair protein XRCC1 isoform X1.
   
 
 0.960
APLF
Aprataxin and PNK-like factor isoform X1.
    
 
 0.951
ERCC4
DNA excision repair protein ERCC-4.
   
 
 0.921
TDP2
Tyrosyl-DNA phosphodiesterase 2.
   
  
 0.906
APTX
Aprataxin isoform X1.
    
 
 0.878
XRCC5
X-ray repair cross-complementing protein 5.
    
 0.869
PNKP
Polynucleotide kinase 3'-phosphatase.
    
 
 0.863
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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