Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HIPK3Homeodomain-interacting protein kinase 3. (1151 aa)    
Predicted Functional Partners:
TP53
Cellular tumor antigen p53.
    
 0.980
RASSF5
Ras association domain-containing protein 5 isoform X1.
    
 0.910
DAXX
Death domain-associated protein 6 isoform X1.
    
 
 0.679
SUMO1
Small ubiquitin-related modifier 1.
    
 0.653
UBE2I
Ubiquitin-conjugating enzyme E2 I.
    
 0.649
MECP2
Methyl CpG binding protein 2.
    
 0.626
NPEPL1
Probable aminopeptidase NPEPL1 isoform X1.
    
 
 0.620
NPAT
Protein NPAT.
    
 
 0.602
EP300
Histone acetyltransferase p300 isoform X1.
   
 0.601
PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 isoform X1.
    
  0.599
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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