Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MAN2C1Alpha-mannosidase 2C1 isoform X1. (1044 aa)    
Predicted Functional Partners:
MAN2B1
Lysosomal alpha-mannosidase isoform X1.
     
 0.959
XRN1
5'-3' exoribonuclease 1 isoform X1.
    
   0.890
ENGASE
endo-beta-N-acetylglucosaminidase.
  
  
 0.748
DNPEP
Aspartyl aminopeptidase.
   
 
 0.734
EOGT
EGF domain-specific O-linked N-acetylglucosamine transferase isoform X1.
      
 0.731
GLYCTK
Glycerate kinase isoform X1.
     
  0.723
MAN1B1
Mannosidase alpha class 1B member 1.
   
  
 0.720
EDEM1
ER degradation-enhancing alpha-mannosidase-like protein 1.
      
 0.695
MIB2
E3 ubiquitin-protein ligase mind-bomb.
   
 
 0.668
OXCT1
Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial.
      
 0.661
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
Server load: low (18%) [HD]