Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
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[Homology]
Score
NRG4Pro-neuregulin-4, membrane-bound isoform isoform X1. (117 aa)    
Predicted Functional Partners:
ERBB4
Receptor tyrosine-protein kinase erbB-4.
    
 0.954
NRG3
Pro-neuregulin-3, membrane-bound isoform-like.
     
 0.751
CITED2
Cbp/p300-interacting transactivator 2.
      
 0.696
SLIT2
Slit homolog 2 protein.
     
 0.644
LOC110080278
Mucin-17-like.
    
 0.605
ENSPVIP00000002638
annotation not available
    
 0.598
NRG1
Pro-neuregulin-1, membrane-bound isoform isoform X1.
    
 0.587
NRG2
Pro-neuregulin-2, membrane-bound isoform.
    
 0.587
GTDC1
Zinc finger E-box-binding homeobox 2 isoform X1.
      
 0.581
ENSPVIP00000026807
annotation not available
      
 0.581
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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