Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ISL2Insulin gene enhancer protein ISL-2. (201 aa)    
Predicted Functional Partners:
ISL1
Insulin gene enhancer protein ISL-1.
 
      0.828
LDB1
LIM domain-binding protein 1 isoform X1.
    
 0.800
LDB2
LIM domain-binding protein 2 isoform X1.
    
 0.800
LHX3
LIM/homeobox protein Lhx3.
    
 0.755
LHX4
LIM/homeobox protein Lhx4.
    
 0.755
TBX20
T-box transcription factor TBX20.
   
 0.691
NKX2-5
Homeobox protein Nkx-2.5.
    
 0.682
LMO4
LIM domain transcription factor LMO4.
    
   0.612
TBX1
T-box transcription factor TBX1.
    
 0.609
ZNF511
Zinc finger protein 511.
    
   0.602
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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