Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
E2F5Transcription factor E2F5 isoform X1. (393 aa)    
Predicted Functional Partners:
TFDP2
Transcription factor Dp-2 isoform X1.
  
 0.991
RBL1
Retinoblastoma-like protein 1.
   
 0.989
RBL2
Retinoblastoma-like protein 2.
   
 0.989
RB1
Retinoblastoma-associated protein.
   
 0.988
TFDP1
Transcription factor Dp-1 isoform X1.
   
 0.982
SMAD4
Mothers against decapentaplegic homolog 4 isoform X1.
    
 0.959
SMAD2
SMAD family member 2.
    
 0.956
LIN9
Protein lin-9 homolog.
    
 0.938
LIN37
Protein lin-37 homolog.
    
 0.910
E2F4
Transcription factor E2F4 isoform X1.
  
  
 
0.904
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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