STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VAV2Vav guanine nucleotide exchange factor 2. (809 aa)    
Predicted Functional Partners:
GRB2
Growth factor receptor-binding protein 2.
    
 0.882
SYK
Tyrosine-protein kinase SYK isoform X1.
   
 0.860
CD19
B-lymphocyte antigen CD19 isoform X1.
   
 0.839
CDC42
Cell division control protein 42 homolog isoform X1.
   
 0.817
ZAP70
Tyrosine-protein kinase ZAP-70.
   
 0.805
NCK2
Cytoplasmic protein NCK2.
    
 0.707
RAC1
Ras-related C3 botulinum toxin substrate 1.
   
 0.682
RAC3
Ras-related C3 botulinum toxin substrate 3.
   
 0.682
RAC2
Ras-related C3 botulinum toxin substrate 2.
   
 0.682
CBL
E3 ubiquitin-protein ligase CBL.
    
 0.681
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.