Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CLDN5Claudin-5. (239 aa)    
Predicted Functional Partners:
CDH5
Cadherin 5, type 2, VE-cadherin.
   
  
 0.995
TJP1
Tight junction protein ZO-1 isoform X1.
   
 0.962
AQP4
Aquaporin-4 isoform X1.
   
  
 0.907
CLDN12
Claudin-12.
     
 0.897
LOC110086804
Claudin-16-like.
    
 0.817
CLDN16
Claudin-16.
    
 0.817
GFAP
Glial fibrillary acidic protein.
      
 0.742
MFSD2A
Sodium-dependent lysophosphatidylcholine symporter 1 isoform X1.
      
 0.737
CLDN7
Claudin-7.
  
  
0.725
CLDN11
Claudin-11.
     
0.719
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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