Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PANX1Pannexin 1. (429 aa)    
Predicted Functional Partners:
PANX2
Pannexin-2 isoform X1.
     
 0.943
P2RX7
Purinergic receptor P2X 7.
     
 0.926
P2RX6
P2X purinoceptor 6.
     
 0.856
CASP7
Caspase 7.
    
 
 0.776
GRPR
Gastrin-releasing peptide receptor.
    
 
 0.727
GJB1
Gap junction beta-1 protein.
      
 0.695
GJA1
Gap junction alpha-1 protein.
      
 0.677
CALHM1
Calcium homeostasis modulator protein 1.
      
 0.660
SUGT1
Suppressor of G2 allele of SKP1.
     
  0.647
LOC110084328
Caspase-7-like.
    
 
 0.645
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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