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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRDM14PR/SET domain 14. (313 aa)    
Predicted Functional Partners:
CBFA2T2
CBFA2/RUNX1 translocation partner 2.
    
 0.873
LOC110077941
Homeobox protein NANOG-like.
    
 0.749
LOC110070984
POU domain, class 5, transcription factor 1-like isoform X1.
   
 0.686
TFAP2C
Transcription factor AP-2 gamma isoform X1.
    
 
 0.682
ALPL
Alkaline phosphatase, tissue-nonspecific isozyme.
   
  
 0.681
DND1
Dead end protein homolog 1.
      
 0.679
NANOS3
Nanos homolog 3.
    
 
 0.614
JUN
Transcription factor AP-1.
   
 0.611
LIN28A
Protein lin-28 homolog A.
   
 0.607
LEF1
Lymphoid enhancer binding factor 1.
    
 0.596
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.