Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PARGPoly(ADP-ribose) glycohydrolase. (996 aa)    
Predicted Functional Partners:
PARP1
Poly [ADP-ribose] polymerase 1.
    
 0.991
XRCC1
DNA repair protein XRCC1 isoform X1.
    
 
 0.973
PARP2
Poly [ADP-ribose] polymerase 2 isoform X1.
    
 0.972
PARP3
Poly [ADP-ribose] polymerase 2/3/4.
    
 0.913
PCNA
Proliferating cell nuclear antigen isoform X1.
    
 
 0.838
ENSPVIP00000001060
annotation not available
    
 0.822
PARP4
Poly [ADP-ribose] polymerase 2/3/4.
    
 0.780
VWA5B2
Von Willebrand factor A domain-containing protein 5B2-like.
    
 0.757
ADPRHL2
Poly(ADP-ribose) glycohydrolase ARH3 isoform X1.
      
 0.742
OARD1
O-acetyl-ADP-ribose deacetylase 1 isoform X1.
      
 0.662
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
Server load: low (8%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.