close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PARGPoly(ADP-ribose) glycohydrolase. (996 aa)    
Predicted Functional Partners:
PARP1
Poly [ADP-ribose] polymerase 1.
    
 0.916
PARP2
Poly [ADP-ribose] polymerase 2 isoform X1.
    
 0.905
PARP3
Poly [ADP-ribose] polymerase 2/3/4.
    
 0.878
PCNA
Proliferating cell nuclear antigen isoform X1.
    
   0.763
ENSPVIP00000001060
annotation not available
    
 0.756
PARP4
Poly [ADP-ribose] polymerase 2/3/4.
    
 0.752
VWA5B2
Von Willebrand factor A domain-containing protein 5B2-like.
    
 0.752
XRCC1
DNA repair protein XRCC1 isoform X1.
      
 0.637
TRPM2
Transient receptor potential cation channel subfamily M member 2.
      
 0.614
POLB
DNA polymerase beta.
     
 0.601
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.