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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OSBPL8Oxysterol-binding protein-related protein 8 isoform X1. (797 aa)    
Predicted Functional Partners:
GM2A
Ganglioside GM2 activator.
      
 0.621
SPTLC1
Serine palmitoyltransferase 1.
      
 0.603
KATNAL2
Katanin p60 ATPase-containing subunit A-like 2 isoform X1.
   
 
 0.583
MBLAC2
Metallo-beta-lactamase domain containing 2.
      
 0.559
THBS4
Thrombospondin 2/3/4/5.
    
 0.493
COMP
Cartilage oligomeric matrix protein isoform X1.
    
 0.493
GFM2
Ribosome-releasing factor 2, mitochondrial isoform X1.
      
 0.479
PHLDA2
Pleckstrin homology-like domain family A member 2.
      
 0.442
SLC22A18
MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 18.
   
  
 0.439
LDLRAP1
Low density lipoprotein receptor adapter protein 1 isoform X1.
      
 0.410
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.