Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
SARDHSarcosine dehydrogenase, mitochondrial isoform X1. (982 aa)    
Predicted Functional Partners:
GLDC
Glycine dehydrogenase (decarboxylating), mitochondrial.
  
 0.991
DHFR
Dihydrofolate reductase isoform X1.
  
 
 0.983
SHMT1
Serine hydroxymethyltransferase, cytosolic isoform X1.
  
 0.978
SHMT2
Serine hydroxymethyltransferase, mitochondrial.
  
 0.978
PIPOX
Peroxisomal sarcosine oxidase isoform X1.
  
 0.973
GNMT
Glycine N-methyltransferase isoform X1.
   
 
 0.969
MTHFD2
Methylenetetrahydrofolate dehydrogenase(NAD+) / 5,10-methenyltetrahydrofolate cyclohydrolase.
  
 
 0.968
MTHFD2L
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like.
  
 
 0.968
MTHFR
Methylenetetrahydrofolate reductase.
  
 
 0.968
LOC110090439
Probable low-specificity L-threonine aldolase 2 isoform X1.
   
 0.959
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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