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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCFD2Multiple coagulation factor deficiency protein 2. (147 aa)    
Predicted Functional Partners:
LMAN1
Lectin, mannose-binding 1.
   
 0.997
F8
Coagulation factor VIII.
     
 0.797
F5
Coagulation factor V (labile factor).
     
 0.683
SEC31A
SEC31 homolog A, COPII coat complex component.
     
 0.674
SEC24C
Protein transport protein Sec24C isoform X1.
     
 0.673
CTSC
Dipeptidyl peptidase 1.
     
 0.643
SEC24D
Protein transport protein Sec24D.
     
 0.637
USO1
General vesicular transport factor p115 isoform X1.
   
 
 0.612
SEC24A
Protein transport protein Sec24A isoform X1.
     
 0.609
GOSR2
Golgi SNAP receptor complex member 2 isoform X1.
   
 
  0.609
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.