Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
TRHDEThyrotropin-releasing hormone-degrading ectoenzyme. (981 aa)    
Predicted Functional Partners:
TRH
Thyrotropin releasing hormone.
      
 0.723
AGT
Angiotensinogen.
   
 0.697
HSPA5
Endoplasmic reticulum chaperone BiP.
    
 0.601
CLN5
Ceroid-lipofuscinosis neuronal protein 5.
      
 0.600
AGTR2
Angiotensin II receptor type 2.
   
 
 0.575
NR3C1
Glucocorticoid receptor.
      
 0.574
PRLR
Prolactin receptor.
      
 0.566
CAMKMT
Calmodulin-lysine N-methyltransferase isoform X1.
    
 
 0.525
RFXANK
Regulatory factor X-associated ankyrin-containing protein.
    
 
 0.486
TMPRSS4
Transmembrane serine protease 4.
    
 0.480
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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