Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
MAP3K12Mitogen-activated protein kinase kinase kinase 12. (880 aa)    
Predicted Functional Partners:
MAP2K7
Mitogen-activated protein kinase kinase 7.
    
0.940
MAP3K13
Mitogen-activated protein kinase kinase kinase 13.
  
  
 
0.902
MYCBP2
E3 ubiquitin-protein ligase MYCBP2 isoform X1.
    
 
 0.819
FBXO45
F-box/SPRY domain-containing protein 1.
    
 
 0.450
CDH26
Cadherin 26.
      
 0.436
DLK1
Protein delta homolog 1 isoform X1.
      
 0.431
CSF1
Macrophage colony-stimulating factor 1.
      
 0.429
MAPK8IP2
Mitogen-activated protein kinase 8 interacting protein 2.
    
 
 0.412
MAPK8IP1
C-Jun-amino-terminal kinase-interacting protein 1 isoform X1.
    
 
 0.412
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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