STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SP1Transcription factor Sp1 isoform X1. (761 aa)    
Predicted Functional Partners:
EP300
Histone acetyltransferase p300 isoform X1.
   
 0.995
CREBBP
CREB-binding protein isoform X1.
   
 0.980
ESR1
Estrogen receptor isoform X1.
    
 0.940
TP53
Cellular tumor antigen p53.
    
 0.934
ESR2
Estrogen receptor beta.
    
 0.824
E2F1
Transcription factor E2F1 isoform X1.
    
 0.804
SMAD2
SMAD family member 2.
    
 0.770
SMAD3
SMAD family member 3.
    
 0.770
JUN
Transcription factor AP-1.
   
 0.763
TBP
Transcription initiation factor TFIID TATA-box-binding protein.
    
 0.762
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.