Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CH25HCholesterol 25-hydroxylase. (294 aa)    
Predicted Functional Partners:
CYP7B1
25/26-hydroxycholesterol 7alpha-hydroxylase.
   
 0.977
CYP51A1
Lanosterol 14-alpha demethylase.
   
 0.972
CYP7A1
Cholesterol 7-alpha-monooxygenase.
   
 0.967
SQLE
Squalene monooxygenase.
   
 
 0.954
DHCR7
7-dehydrocholesterol reductase isoform X1.
   
 0.952
LOC110089659
Cholesterol 24-hydroxylase-like.
   
 0.942
LOC110089661
Cholesterol 24-hydroxylase-like.
   
 0.942
SC5D
Delta7-sterol 5-desaturase.
   
 
 0.926
DHCR24
Delta(24)-sterol reductase.
   
 
 0.924
CYP27A1
Sterol 26-hydroxylase, mitochondrial.
   
 0.918
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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