Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ROBO4Roundabout, axon guidance receptor 4. (962 aa)    
Predicted Functional Partners:
SLIT2
Slit homolog 2 protein.
   
 0.823
SLIT1
Slit homolog 1 protein.
   
 0.752
SLIT3
Slit homolog 3 protein isoform X1.
   
 0.681
ENSPVIP00000029417
annotation not available
   
 0.681
NYX
Nyctalopin.
   
 0.623
GDNF
Glial cell derived neurotrophic factor.
     
 0.561
ABL1
Tyrosine-protein kinase ABL1 isoform X1.
   
 0.521
ABL2
Abelson tyrosine-protein kinase 2.
   
 0.521
NRP1
Neuropilin-1 isoform X1.
     
 0.491
SDC2
Syndecan-2 isoform X1.
    
 
 0.454
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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