STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APTXAprataxin isoform X1. (348 aa)    
Predicted Functional Partners:
XRCC1
DNA repair protein XRCC1 isoform X1.
    
 
 0.969
PARP1
Poly [ADP-ribose] polymerase 1.
   
 
 0.885
TDP1
Tyrosyl-DNA phosphodiesterase 1 isoform X1.
    
 
 0.878
APLF
Aprataxin and PNK-like factor isoform X1.
      
 0.853
PARP2
Poly [ADP-ribose] polymerase 2 isoform X1.
   
 
 0.819
LIG3
DNA ligase 3.
    
 
 0.806
KLF6
Krueppel-like factor 6/7.
      
 0.782
LIG4
DNA ligase 4 isoform X1.
    
 
 0.715
SETX
Senataxin.
   
  
 0.706
PNKP
Polynucleotide kinase 3'-phosphatase.
    
 
 0.700
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.