Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
PRAG1Tyrosine-protein kinase SgK223-like. (1360 aa)    
Predicted Functional Partners:
FAM20A
Pseudokinase FAM20A.
      
 0.801
STIM1
Stromal interaction molecule 1 isoform X1.
      
 0.646
GJA5
Gap junction alpha-5 protein.
      
 0.621
ALDH2
Aldehyde dehydrogenase, mitochondrial.
      
 0.617
PPP2R5B
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform.
      
 0.617
MFHAS1
Malignant fibrous histiocytoma-amplified sequence 1.
      
 0.616
IQCG
IQ domain-containing protein G.
      
 0.590
PHGDH
D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase.
      
 0.572
ENSPVIP00000033725
annotation not available
      
 0.569
PTPRE
Receptor-type tyrosine-protein phosphatase epsilon isoform X1.
      
 0.542
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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