Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
SIN3APaired amphipathic helix protein Sin3a. (1302 aa)    
Predicted Functional Partners:
SKI
Ski oncogene isoform X1.
   
 0.967
HDAC2
Histone deacetylase 2 isoform X1.
   
 0.966
HDAC1
Histone deacetylase 1/2.
   
 0.966
NCOR1
Nuclear receptor corepressor 1 isoform X1.
   
 0.960
MECP2
Methyl CpG binding protein 2.
    
 0.941
ARID4A
AT-rich interactive domain-containing protein 4A isoform X1.
   
 0.924
ARID4B
AT-rich interactive domain-containing protein 4B isoform X1.
   
 0.924
SUDS3
Sin3 histone deacetylase corepressor complex component SDS3.
   
 0.918
SMAD4
Mothers against decapentaplegic homolog 4 isoform X1.
    
 0.907
PHF12
PHD finger protein 12.
   
 
 0.884
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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