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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RUFY4RUN and FYVE domain-containing protein 4 isoform X1. (881 aa)    
Predicted Functional Partners:
RAB7B
Ras-related protein Rab-7B.
     
 0.903
RAB7A
Ras-related protein Rab-7A.
    
  0.902
LOC110078636
Ras-related protein Rab-7a-like isoform X1.
     
 0.901
FYCO1
FYVE and coiled-coil domain-containing protein 1 isoform X1.
     
 
0.900
RUFY2
RUN and FYVE domain-containing protein 2 isoform X1.
    
 
 0.587
ZNF142
Zinc finger protein 142.
      
 0.563
SMDT1
Essential MCU regulator, mitochondrial.
     
 0.545
STK36
Serine/threonine-protein kinase 36 isoform X1.
      
 0.514
MICU2
Calcium uptake protein 2, mitochondrial isoform X1.
   
 0.452
MICU1
Calcium uptake protein 1, mitochondrial isoform X1.
   
 0.452
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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