Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
XRCC5X-ray repair cross-complementing protein 5. (761 aa)    
Predicted Functional Partners:
XRCC6
X-ray repair cross-complementing protein 6 isoform X1.
   
 0.999
PRKDC
LOW QUALITY PROTEIN: DNA-dependent protein kinase catalytic subunit.
   
 0.997
LIG4
DNA ligase 4 isoform X1.
   
 0.989
DCLRE1C
DNA cross-link repair 1C protein.
    
 0.983
WRN
Werner syndrome ATP-dependent helicase isoform X1.
   
 
 0.977
MRE11
Double-strand break repair protein MRE11.
   
 0.968
PARP1
Poly [ADP-ribose] polymerase 1.
   
 
 0.962
APLF
Aprataxin and PNK-like factor isoform X1.
    
 
 0.956
PCNA
Proliferating cell nuclear antigen isoform X1.
    
 
 0.950
POLL
DNA polymerase lambda isoform X1.
    
 0.941
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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