LMNA protein (Pogona vitticeps) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

LMNA

Lamin A/C. (719 aa)

Predicted Functional Partners:

CASP6

0.963

ENSPVIP00000033456

0.904

SUN2

0.865

EMD

0.855

SUN1

0.851

LEMD3

0.752

BANF2

0.745

BANF1

0.745

LOC110079894

0.702

NUP153

0.695

Your Current Organism:

Pogona vitticeps

NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BANF1	EMD	ENSPVIP00000025857	ENSPVIP00000024299	Barrier-to-autointegration factor.	Emerin isoform X1.	0.970
BANF1	ENSPVIP00000033456	ENSPVIP00000025857	ENSPVIP00000033456	Barrier-to-autointegration factor.	annotation not available	0.636
BANF1	LEMD3	ENSPVIP00000025857	ENSPVIP00000000200	Barrier-to-autointegration factor.	LEM domain containing 3.	0.852
BANF1	LMNA	ENSPVIP00000025857	ENSPVIP00000009387	Barrier-to-autointegration factor.	Lamin A/C.	0.745
BANF2	EMD	ENSPVIP00000011530	ENSPVIP00000024299	Barrier-to-autointegration factor-like protein isoform X1.	Emerin isoform X1.	0.970
BANF2	ENSPVIP00000033456	ENSPVIP00000011530	ENSPVIP00000033456	Barrier-to-autointegration factor-like protein isoform X1.	annotation not available	0.636
BANF2	LEMD3	ENSPVIP00000011530	ENSPVIP00000000200	Barrier-to-autointegration factor-like protein isoform X1.	LEM domain containing 3.	0.852
BANF2	LMNA	ENSPVIP00000011530	ENSPVIP00000009387	Barrier-to-autointegration factor-like protein isoform X1.	Lamin A/C.	0.745
CASP6	ENSPVIP00000033456	ENSPVIP00000005047	ENSPVIP00000033456	Caspase 6.	annotation not available	0.946
CASP6	LMNA	ENSPVIP00000005047	ENSPVIP00000009387	Caspase 6.	Lamin A/C.	0.963
EMD	BANF1	ENSPVIP00000024299	ENSPVIP00000025857	Emerin isoform X1.	Barrier-to-autointegration factor.	0.970
EMD	BANF2	ENSPVIP00000024299	ENSPVIP00000011530	Emerin isoform X1.	Barrier-to-autointegration factor-like protein isoform X1.	0.970
EMD	ENSPVIP00000033456	ENSPVIP00000024299	ENSPVIP00000033456	Emerin isoform X1.	annotation not available	0.793
EMD	LEMD3	ENSPVIP00000024299	ENSPVIP00000000200	Emerin isoform X1.	LEM domain containing 3.	0.892
EMD	LMNA	ENSPVIP00000024299	ENSPVIP00000009387	Emerin isoform X1.	Lamin A/C.	0.855
EMD	LOC110079894	ENSPVIP00000024299	ENSPVIP00000005130	Emerin isoform X1.	SUN domain-containing protein 3-like.	0.663
EMD	NUP153	ENSPVIP00000024299	ENSPVIP00000006230	Emerin isoform X1.	Nuclear pore complex protein Nup153 isoform X1.	0.571
EMD	SUN1	ENSPVIP00000024299	ENSPVIP00000002361	Emerin isoform X1.	SUN domain-containing protein 1 isoform X1.	0.819
EMD	SUN2	ENSPVIP00000024299	ENSPVIP00000033717	Emerin isoform X1.	Sad1 and UNC84 domain containing 2.	0.663
ENSPVIP00000033456	BANF1	ENSPVIP00000033456	ENSPVIP00000025857	annotation not available	Barrier-to-autointegration factor.	0.636