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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTGFRProstaglandin F2-alpha receptor. (364 aa)    
Predicted Functional Partners:
GNA11
Guanine nucleotide-binding protein subunit alpha-11.
    
  0.817
LOC110076012
Guanine nucleotide-binding protein G(q) subunit alpha.
    
  0.817
GNA14
Guanine nucleotide-binding protein subunit alpha-14-like.
    
  0.817
GNA15
Guanine nucleotide-binding protein subunit alpha-15 isoform X1.
    
  0.814
ZFYVE9
MAD, mothers against decapentaplegic interacting protein.
      
 0.679
CDC42
Cell division control protein 42 homolog isoform X1.
     
 0.563
PTGFRN
Prostaglandin F2 receptor negative regulator.
      
 0.529
FERMT2
Fermitin family homolog 2 isoform X1.
      
 0.487
FERMT1
Fermitin family homolog 1.
      
 0.487
LOC110089251
Gonadotropin-releasing hormone II receptor-like.
      
 0.412
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.