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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EME1Crossover junction endonuclease EME1. (350 aa)    
Predicted Functional Partners:
MUS81
MUS81 structure-specific endonuclease subunit.
   
 0.997
SLX4
Structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12).
    
 0.981
RAD51C
DNA repair protein RAD51 homolog 3.
     
 0.915
EXO1
Exonuclease 1 isoform X1.
   
 0.874
RAG1
V(D)J recombination-activating protein 1.
    
  0.848
SLX1A
Structure-specific endonuclease subunit SLX1 isoform X1.
    
 0.830
FAN1
Fanconi-associated nuclease 1.
     
 0.827
LOC110091408
Asparagine--tRNA ligase, cytoplasmic-like.
    
 0.825
NARS1
Asparagine--tRNA ligase, cytoplasmic.
    
 0.825
ERCC4
DNA excision repair protein ERCC-4.
    
 0.818
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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