Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EME1Crossover junction endonuclease EME1. (350 aa)    
Predicted Functional Partners:
MUS81
MUS81 structure-specific endonuclease subunit.
   
 0.999
SLX4
Structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12).
    
 0.994
SLX1A
Structure-specific endonuclease subunit SLX1 isoform X1.
    
 0.963
ERCC1
DNA excision repair protein ERCC-1 isoform X1.
    
 0.952
RMI2
RecQ-mediated genome instability protein 2.
   
 
 0.905
RAD51
DNA repair protein RAD51 homolog 1.
   
 
 0.902
FANCD2
FA complementation group D2.
   
 
 0.886
BRCA1
Breast cancer type 1 susceptibility protein.
   
 0.881
EXO1
Exonuclease 1 isoform X1.
   
 0.875
DCLRE1A
DNA cross-link repair 1A protein isoform X1.
     
 0.873
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.