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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AUTS2Autism susceptibility gene 2 protein. (1100 aa)    
Predicted Functional Partners:
PCGF5
Polycomb group RING finger protein 5 isoform X1.
    
 0.939
PCGF3
Polycomb group RING finger protein 3.
    
 0.924
CSNK2B
Casein kinase II subunit beta isoform X1.
    
 0.849
PCGF6
Polycomb group RING finger protein 6.
    
 0.824
PCGF1
Polycomb group RING finger protein 1.
    
 0.770
CHEK2
Serine/threonine-protein kinase CHEK2.
   
 0.731
CHEK1
Serine/threonine-protein kinase CHEK1.
   
 0.703
RERE
Arginine-glutamic acid dipeptide repeats.
   
 
 0.691
DOCK1
Dedicator of cytokinesis protein 1 isoform X1.
    
 
 0.680
FEZ1
Fasciculation and elongation protein zeta-1 isoform X1.
      
 0.679
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.