Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
UBA3NEDD8-activating enzyme E1 catalytic subunit isoform X1. (504 aa)    
Predicted Functional Partners:
NAE1
NEDD8 activating enzyme E1 subunit 1.
   
 0.998
NEDD8
Ubiquitin-like protein Nedd8.
    
 0.995
UBE2F
NEDD8-conjugating enzyme UBE2F isoform X1.
    
 0.985
CUL1
Cullin-1 isoform X1.
   
 0.942
UBE2H
Ubiquitin-conjugating enzyme E2 H.
    
 0.940
CUL5
Cullin-5 isoform X1.
   
 0.930
CUL3
Cullin-3 isoform X1.
   
 0.906
LOC110071800
Ubiquitin-conjugating enzyme E2 variant 1.
   
 0.878
RBX1
E3 ubiquitin-protein ligase RBX1.
    
 0.861
CUL2
Cullin-2 isoform X1.
   
 0.860
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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