Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
SPRY4Sprouty RTK signaling antagonist 4. (306 aa)    
Predicted Functional Partners:
TESK1
Testis associated actin remodelling kinase 1.
    
 0.824
TESK2
Dual specificity testis-specific protein kinase 2.
    
 0.705
IL17RD
Interleukin-17 receptor D isoform X1.
   
  
 0.696
CBL
E3 ubiquitin-protein ligase CBL.
    
 0.629
CBLB
E3 ubiquitin-protein ligase CBL-B isoform X1.
    
 0.629
CBLC
E3 ubiquitin-protein ligase CBL-C.
    
 0.629
FGF8
Fibroblast growth factor 8 isoform X1.
   
  
 0.622
ETV4
ETS variant transcription factor 4.
      
 0.574
LAPTM4B
Lysosomal-associated transmembrane protein 4B isoform X1.
    
   0.556
GRB2
Growth factor receptor-binding protein 2.
    
 0.550
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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