Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LRRC14Leucine-rich repeat-containing protein 14. (509 aa)    
Predicted Functional Partners:
CHUK
Inhibitor of nuclear factor kappa-B kinase subunit alpha.
    
  0.937
CUL2
Cullin-2 isoform X1.
    
 
 0.877
COPS5
COP9 signalosome complex subunit 5.
    
   0.876
IKBKB
Inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1.
    
  0.802
COPS6
COP9 signalosome complex subunit 6.
    
   0.769
ALG12
Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase isoform X1.
   
  
 0.731
WDR74
Ribosome biogenesis protein NSA1.
      
 0.695
PIK3IP1
Phosphoinositide-3-kinase-interacting protein 1.
      
 0.692
PREPL
Prolyl endopeptidase-like.
      
 0.643
MRPS12
28S ribosomal protein S12, mitochondrial.
   
  
 0.582
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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