Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
MAP2K2Dual specificity mitogen-activated protein kinase kinase 2. (402 aa)    
Predicted Functional Partners:
BRAF
B-Raf proto-oncogene serine/threonine-protein kinase.
   
0.989
ARAF
A-Raf proto-oncogene serine/threonine-protein kinase.
   
0.979
RAF1
RAF proto-oncogene serine/threonine-protein kinase isoform X1.
   
0.979
MAPK1
Mitogen-activated protein kinase 1/3.
   
0.976
MAPK3
Mitogen-activated protein kinase 1/3.
   
0.976
MAP3K8
Mitogen-activated protein kinase kinase kinase 8.
  
 
0.974
LAMTOR3
Ragulator complex protein LAMTOR3.
   
 0.970
MAP3K1
Mitogen-activated protein kinase kinase kinase 1.
    
0.967
MAP2K1
Mitogen-activated protein kinase kinase 1.
  
  
 
0.901
YWHAB
14-3-3 protein beta/theta/zeta.
   
 0.855
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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