STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PIAS4Protein inhibitor of activated STAT 4. (478 aa)    
Predicted Functional Partners:
UBE2I
Ubiquitin-conjugating enzyme E2 I.
    
 0.994
RNF168
E3 ubiquitin-protein ligase RNF168 isoform X1.
   
 
 0.975
SUMO1
Small ubiquitin-related modifier 1.
    
 0.973
PARP1
Poly [ADP-ribose] polymerase 1.
    
 0.935
SUMO2
Small ubiquitin-related modifier 2.
    
 0.917
ENSPVIP00000028426
annotation not available
    
 0.917
BRCA1
Breast cancer type 1 susceptibility protein.
    
 0.871
TP53BP1
Tumor suppressor p53-binding protein 1.
    
 0.827
RNF8
E3 ubiquitin-protein ligase RNF8 isoform X1.
     
 0.788
VHL
Von Hippel-Lindau disease tumor suppressor.
    
  0.760
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.