STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NKX2-5Homeobox protein Nkx-2.5. (303 aa)    
Predicted Functional Partners:
GATA5
Transcription factor GATA-5.
   
 0.849
GATA4
Transcription factor GATA-4-like.
   
 0.849
TBX5
T-box transcription factor TBX5.
   
 
 0.818
TBX4
T-box transcription factor TBX4 isoform X1.
   
 
 0.818
GATA6
Transcription factor GATA-6 isoform X1.
   
 0.807
WT1
Wilms tumor protein isoform X1.
      
 0.778
MEF2A
Myocyte-specific enhancer factor 2A isoform X1.
    
 
 0.774
MEF2C
Myocyte enhancer factor 2C.
    
 
 0.774
HAND2
Heart- and neural crest derivatives-expressed protein 2.
   
 
 0.768
EDN1
Endothelin-1.
      
 0.768
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.