STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
POLHDNA polymerase eta. (706 aa)    
Predicted Functional Partners:
PCNA
Proliferating cell nuclear antigen isoform X1.
   
 0.998
REV1
DNA repair protein REV1 isoform X1.
   
0.990
WRN
Werner syndrome ATP-dependent helicase isoform X1.
  
 0.980
REV3L
DNA polymerase zeta catalytic subunit.
   
 0.974
MAD2L2
Mitotic spindle assembly checkpoint protein MAD2B.
   
 0.951
UBC
Polyubiquitin-C.
    
 0.930
RAD18
RAD18 E3 ubiquitin protein ligase.
    
 
 0.923
POLD1
DNA polymerase delta catalytic subunit.
   
 0.899
RAD51
DNA repair protein RAD51 homolog 1.
  
 0.855
RPS27A
Ribosomal protein S27a.
    
  0.848
Your Current Organism:
Pogona vitticeps
NCBI taxonomy Id: 103695
Other names: P. vitticeps, ZMB 30101, central bearded dragon
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.