STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dnaECOG0587 DNA polymerase III, alpha subunit. (976 aa)    
Predicted Functional Partners:
dnaX
DNA-directed DNA polymerase; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
  
 0.999
EGV00094.1
DNA polymerase iii subunit delta; COG0470 ATPase involved in DNA replication.
  
 0.999
EGV00145.1
COG1466 DNA polymerase III, delta subunit.
  
 0.999
EGV00186.1
Hypothetical protein; COG0210 Superfamily I DNA and RNA helicases.
  
 0.999
EGV00465.1
COG0592 DNA polymerase sliding clamp subunit (PCNA homolog).
    
 0.999
EGV00158.1
COG0629 Single-stranded DNA-binding protein.
   
 0.993
polC
DNA polymerase III PolC; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
 
  
0.990
EGV00291.1
DNA-directed DNA polymerase; COG0258 5'-3' exonuclease (including N-terminal domain of PolI).
 
 
 0.971
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.826
EGV00294.1
Uvrabc system protein c; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
    
 0.800
Your Current Organism:
Mycoplasma columbinum
NCBI taxonomy Id: 1037410
Other names: M. columbinum SF7, Mycoplasma columbinum SF7, Mycoplasma columbinum str. SF7, Mycoplasma columbinum strain SF7
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