STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
polCDNA polymerase III PolC; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (1457 aa)    
Predicted Functional Partners:
EGV00186.1
Hypothetical protein; COG0210 Superfamily I DNA and RNA helicases.
  
 
 0.999
dnaE
COG0587 DNA polymerase III, alpha subunit.
 
  
0.990
dnaX
DNA-directed DNA polymerase; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
  
 0.989
EGV00465.1
COG0592 DNA polymerase sliding clamp subunit (PCNA homolog).
   
 0.989
EGV00145.1
COG1466 DNA polymerase III, delta subunit.
    
 0.985
EGV00094.1
DNA polymerase iii subunit delta; COG0470 ATPase involved in DNA replication.
  
 0.984
EGV00291.1
DNA-directed DNA polymerase; COG0258 5'-3' exonuclease (including N-terminal domain of PolI).
   
 
 0.821
whiA
Hypothetical protein; Involved in cell division and chromosome segregation.
 
     0.755
EGV00294.1
Uvrabc system protein c; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
 
  
 0.720
EGV00063.1
COG0210 Superfamily I DNA and RNA helicases.
  
 
 0.704
Your Current Organism:
Mycoplasma columbinum
NCBI taxonomy Id: 1037410
Other names: M. columbinum SF7, Mycoplasma columbinum SF7, Mycoplasma columbinum str. SF7, Mycoplasma columbinum strain SF7
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.