STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APH02261.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (431 aa)    
Predicted Functional Partners:
APH03186.1
Adenine glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.799
disA
DNA integrity scanning protein DisA; Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process.
       0.773
radA
DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
       0.762
guaA
GMP synthetase; Catalyzes the synthesis of GMP from XMP.
    
  0.690
APH01431.1
Single-stranded DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.670
APH02257.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.607
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
  0.605
APH00253.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.578
APH01356.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.551
APH02648.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.520
Your Current Organism:
Janibacter terrae
NCBI taxonomy Id: 103817
Other names: ATCC BAA-130, CCUG 45369, CIP 107018, DSM 13876, DSM 13953 [[Janibacter brevis Imamura et al. 2000]], J. terrae, JCM 10705, JCM 12887 [[Janibacter brevis Imamura et al. 2000]], Janibacter brevis, Janibacter brevis Imamura et al. 2000, Janibacter terrae Yoon et al. 2000 emend. Lang et al. 2003, KCCM 80001, KCTC 19953, NBRC 107853, strain 10N [[Janibacter brevis Imamura et al. 2000]], strain CS12
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