STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
iscXHypothetical protein. (64 aa)    
Predicted Functional Partners:
fdx_2
2Fe-2S ferredoxin.
 
  
 0.990
hscB
Hypothetical protein; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family.
 
  
 0.977
hscA
Chaperone protein HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
 
  
 0.966
iscU
NifU-like protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
 
 
 0.961
iscS
Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
 
 
 0.920
iscA
Iron-binding protein IscA; Belongs to the HesB/IscA family.
 
  
 0.901
thcC_1
Rhodocoxin.
  
  
 0.775
thcC_2
Rhodocoxin.
  
  
 0.775
cyaY
Frataxin-like protein; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.
  
  
 0.743
iscR
HTH-type transcriptional regulator IscR.
  
  
 0.681
Your Current Organism:
Bordetella hinzii
NCBI taxonomy Id: 103855
Other names: ATCC 51783, B. hinzii, CCUG 33847, CIP 104527, DSM 11333, JCM 15550, LMG 13501, LMG:13501, NCTC 13199, strain TC58
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.