STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CysG-2uroporphyrinogen-III methylase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the precorrin methyltransferase family. (798 aa)    
Predicted Functional Partners:
HemB
Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
 
 0.999
HemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
  
 0.997
CysG
Siroheme synthase; Precorrin-2 oxidase/ferrochelatase domain.
 
 0.997
HemL
Glutamate-1-semialdehyde aminotransferase.
 
  
 0.986
BAK46431.1
Hypothetical protein; Belongs to the uroporphyrinogen decarboxylase family.
  
 0.972
BAK46706.1
Hypothetical protein; Belongs to the uroporphyrinogen decarboxylase family.
  
 0.972
CobF
Precorrin-2 methylase; Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway.
 
 
 0.968
BAK47067.1
Hypothetical protein; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
 
  
 0.922
CysN
GTPase; Catalyzes the synthesis of activated sulfate. Belongs to the APS kinase family.
  
  
 0.905
CobK
Precorrin-6x reductase.
  
 0.902
Your Current Organism:
Clostridium sp. SY8519
NCBI taxonomy Id: 1042156
Other names: C. sp. SY8519
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