STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PMG11_008676,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (267 aa)    
Predicted Functional Partners:
RIB5
Putative Riboflavin synthase alpha chain.
 
 0.998
RIB3
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
 
 
 0.994
PMG11_04093
Putative GTP cyclohydrolase-2.
 
 
 0.981
PMG11_08083
Putative Riboflavin kinase.
  
 
 0.968
PMG11_08085
Uncharacterized protein.
  
 
 0.968
PMG11_02783
Putative GTP cyclohydrolase-2.
  
 
 0.949
PMG11_04468
F-box domain-containing protein.
  
 
 0.949
PMG11_07539
S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.
  
 
 0.946
PMG11_09580
PH domain-containing protein.
  
 0.908
PMG11_10779
Coronin; Belongs to the WD repeat coronin family.
  
 0.908
Your Current Organism:
Penicillium brasilianum
NCBI taxonomy Id: 104259
Other names: ATCC 12072, CBS 253.55, FRR 3466, P. brasilianum, Penicillium sp. 028M, Penicillium sp. FKI-3368, QM 6947
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