STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PMG11_06124DNA helicase; Belongs to the MCM family. (898 aa)    
Predicted Functional Partners:
PMG11_00527
DNA helicase; Belongs to the MCM family.
  
0.999
PMG11_07085
DNA helicase; Belongs to the MCM family.
  
0.999
PMG11_07547
Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
  
 0.999
MCM7
DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]
  
0.999
PMG11_08549
DNA helicase; Belongs to the MCM family.
  
0.999
PMG11_08855
Uncharacterized protein.
   
 0.999
PMG11_09668
DNA helicase; Belongs to the MCM family.
  
0.999
PMG11_03413
Cell division control protein; Belongs to the CDC6/cdc18 family.
   
 0.999
PMG11_03785
Putative Cell division control protein 45.
   
 0.999
PMG11_00246
AAA domain-containing protein.
   
 0.998
Your Current Organism:
Penicillium brasilianum
NCBI taxonomy Id: 104259
Other names: ATCC 12072, CBS 253.55, FRR 3466, P. brasilianum, Penicillium sp. 028M, Penicillium sp. FKI-3368, QM 6947
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